There was a news article a few days ago, saying that some researcher had discovered that migraine sufferers have thicker cortexes than the norm, and MS patients had thinner than the norm. It was conjectured that the thicker ones might have to do with an increased susceptibility to pain.
I don’t have MS, but one autoimmune neurological disease is as good as another; my ability to feel pain in some areas has become impaired. I said to my husband, who gets migraines, “So. That means you’re thick headed and I’m a numb skull?”